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Last updated: 2017/2/19
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POLR2A (phospho S5) monoclonal antibody, clone 8A7

  • Catalog # : MAB2441
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic phosphopeptide of POLR2A.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding S5 of human POLR2A.
  • Sequence:
  • YSPTSPS
  • Host:
  • Mouse
  • Reactivity:
  • Human, Yeast
  • Specificity:
  • recognizes the phosphorylated (Ser5) form of POLR2A in human and S. cerevisiae.
  • Form:
  • Liquid
  • Isotype:
  • IgM
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunofluorescence
  • ELISA
  • Application Image
  • Western Blot
  • Immunofluorescence
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5430
  • Gene Name:
  • POLR2A
  • Gene Alias:
  • MGC75453,POLR2,POLRA,RPB1,RPBh1,RPO2,RPOL2,RpIILS,hRPB220,hsRPB1
  • Gene Description:
  • polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • Gene Summary:
  • This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq
  • Other Designations:
  • DNA directed RNA polymerase II polypeptide A,DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit,polymerase (RNA) II (DNA directed) polypeptide A (220kD)
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