BFSP1 monoclonal antibody, clone FIL-7B10
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against native BFSP1.
Immunogen
Native from human and bovine lens filament enriched fraction (plasma membrane-cytoskeleton complex).
Host
Mouse
Theoretical MW (kDa)
115
Reactivity
Bovine, Human
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (Frozen sections) (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 1.2% sodium acetate (2 mg BSA, 0.01 mg sodium azide)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Immunohistochemistry (Frozen sections)
-
Gene Info — BFSP1
Entrez GeneID
631GeneBank Accession#
BC041483Protein Accession#
AAH41483Gene Name
BFSP1
Gene Alias
CP115, CP94, FILENSIN, LIFL-H
Gene Description
beaded filament structural protein 1, filensin
Gene Ontology
HyperlinkGene Summary
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000030329|cytoskeletal protein, 115 KD|filensin
-
Gene Info — BFSP1
-
Interactome
-
Publication Reference
-
Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1.
Rendtorff ND, Hansen C, Silahtaroglu A, Henriksen KF, Tommerup N.
Genomics 1998 Oct; 53(1):114.
-
Chromosomal locations of the genes for the beaded filament proteins CP 115 and CP 47.
Hess JF, Casselman JT, FitzGerald PG.
Current Eye Research 1995 Jan; 14(1):11.
-
Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com