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ABCC1 monoclonal antibody, clone IU2H10

  • Catalog # : MAB2388
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of ABCC1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 1-33 of human ABCC1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody is specific to MRP1 protein.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris-glycine, 150 mM NaCl
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of MRP1 using ABCC1 monoclonal antibody, clone IU2H10 (Cat # MAB2388) on vector-transfected HEK293 cells (lane1), MRP1-transfected cells, prep1 (lane 2) and MRP1-transfected cells, prep2 (Lane 3). The lower band is a degradation product.
  • Immunofluorescence
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 4363
  • Gene Name:
  • ABCC1
  • Gene Alias:
  • ABC29,ABCC,DKFZp686N04233,DKFZp781G125,GS-X,MRP,MRP1
  • Gene Description:
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette, sub-family C, member 1,LTC4 transporter,OTTHUMP00000045904,leukotriene C(4) transporter,multidrug resistance protein,multiple drug resistance protein 1,multiple drug resistance-associated protein
  • Gene Pathway
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