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Last updated: 2016/11/27
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RAD51C monoclonal antibody, clone 2H11/6

  • Catalog # : MAB2387
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant RAD51C.
  • Immunogen:
  • Recombinant His fusion protein corresponding to human RAD51C.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody is specific to Rad51C.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • RAD51C detected in HEK293 lysate using RAD51C monoclonal antibody, clone 2H11/6 (Cat # MAB2387). Photo courtesy of B.T. Bennett & K. Knight, University of Massachusetts Medical School.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5889
  • Gene Name:
  • RAD51C
  • Gene Alias:
  • MGC104277,RAD51L2
  • Gene Description:
  • RAD51 homolog C (S. cerevisiae)
  • Gene Summary:
  • This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • DNA repair protein RAD51 homolog 3,RAD51 homolog C,RAD51 homolog C, isoform 1,yeast RAD51 homolog 3
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