AIP monoclonal antibody, clone 35-2
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of AIP in mouse lung lysates (30 ug) using AIP monoclonal antibody, clone 35-2 (Cat # MAB2382) at 1 : 500 with a 1 second exposure.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant AIP.
Immunogen
Recombinant protein corresponding to human AIP.
Host
Mouse
Reactivity
Human, Mouse, Rat
Specificity
This antibody is specific to ARA9.
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In tissue culture supernatant (0.09% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of AIP in mouse lung lysates (30 ug) using AIP monoclonal antibody, clone 35-2 (Cat # MAB2382) at 1 : 500 with a 1 second exposure.Immunoprecipitation
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Gene Info — AIP
Entrez GeneID
9049Gene Name
AIP
Gene Alias
ARA9, FKBP16, FKBP37, SMTPHN, XAP2
Gene Description
aryl hydrocarbon receptor interacting protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. [provided by RefSeq
Other Designations
HBV-X associated protein|aryl hydrocarbon receptor-interacting protein
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Interactome
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Disease
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Publication Reference
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Role of endogenous XAP2 protein on the localization and nucleocytoplasmic shuttling of the endogenous mouse Ahb-1 receptor in the presence and absence of ligand.
Pollenz RS, Wilson SE, Dougherty EJ.
Molecular Pharmacology 2006 Oct; 70(4):1369.
Application：WB, Human, Hepa-1 cells.
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The aryl hydrocarbon (Ah) receptor transcriptional regulator hepatitis B virus X-associated protein 2 antagonizes p23 binding to Ah receptor-Hsp90 complexes and is dispensable for receptor function.
Hollingshead BD, Petrulis JR, Perdew GH.
The Journal of Biological Chemistry 2004 Oct; 279(44):45652.
Application：IP, WB, Monkey, COS-1 cells.
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Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2.
Petrulis JR, Hord NG, Perdew GH.
The Journal of Biological Chemistry 2000 Dec; 275(48):37448.
Application：WB-Ce, WB-Tr, Monkey, COS-1 cells.
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Characterization of the Ah receptor-associated protein, ARA9.
Carver LA, LaPres JJ, Jain S, Dunham EE, Bradfield CA.
The Journal of Biological Chemistry 1998 Dec; 273(50):33580.
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Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo.
Carver LA, Bradfield CA.
The Journal of Biological Chemistry 1997 Apr; 272(17):11452.
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Role of endogenous XAP2 protein on the localization and nucleocytoplasmic shuttling of the endogenous mouse Ahb-1 receptor in the presence and absence of ligand.
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