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Last updated: 2018/1/21
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UCHL1 monoclonal antibody, clone BH7

  • Catalog # : MAB2381
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant UCHL1.
  • Immunogen:
  • Recombinant protein corresponding to full length human UCHL1.
  • Host:
  • Mouse
  • Reactivity:
  • Bovine, Human, Rat
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Immunofluorescence (1:1000)
    Western Blot (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant (10 mM sodium azide)
  • Storage Instruction:
  • Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blots of UCHL1 in whole cell homogenate of bovine brain stained with UCHL1 monoclonal antibody, clone BH7 (Cat # MAB2381) (right most lane), and two other monoclonal antibodies reactive with UCHL1 (left and central lane).
  • Immunofluorescence
  • Immunofluorescence
  • Shows human embryonic kidney cell line 293 stained with mouse monoclonal to UCHL1 monoclonal antibody, clone BH7 (Cat # MAB2381) (green) and rabbit antibody to neurofilament NF-M (red). Blue is a DNA stain. Note that some of the Hek293 cells, which perhaps surprisingly have some properties of neuronal lineage cells (4), are beginning to express both UCHL1 and NF-M, both markers of neurons. The majority of cells, however express neither protein. Note that the UCHL1 is cytoplasmic and diffuse while the NF-M is concentrated in cytoplasmic filaments.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7345
  • Gene Name:
  • UCHL1
  • Gene Alias:
  • PARK5,PGP9.5,Uch-L1
  • Gene Description:
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
  • Gene Summary:
  • The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease
  • Other Designations:
  • ubiquitin C-terminal esterase L1,ubiquitin carboxyl-terminal esterase L1,ubiquitin thiolesterase L1
  • Gene Pathway
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