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RNASEL monoclonal antibody, clone 2E9

  • Catalog # : MAB2378
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant RNASEL.
  • Immunogen:
  • Recombinant protein corresponding to full length human RNASEL.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Primates
  • Specificity:
  • This antibody is specific to human RNaseL.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (1:1000-1:4000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C or -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 2.
  • Germline mutations in the ribonuclease L gene in families showing linkage with HPC1.
    Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing C, Gillanders E, Hu P, Bujnovszky P, Makalowska I, Baffoe-Bonnie A, Faith D, Smith J, Stephan D, Wiley K, Brownstein M, Gildea D, Kelly B, Jenkins R, Hostetter G, Matikainen M, Schleutker J, Klinger K, Connors T, Xiang Y, Wang Z, De Marzo A, Papadopoulos N, Kallioniemi OP, Burk R, Meyers D, Gronberg H, Meltzer P, Silverman R, Bailey-Wilson J, Walsh P, Isaacs W, Trent J.Nat Genet. 2002 Feb;30(2):181-4. Epub 2002 Jan 22.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of RNASEL in transfected cells (0.1 ug) and Hey1B (100 ug), using RNASEL monoclonal antibody, clone 2E9 (Cat # MAB2378).
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of RNASEL in insect cell extracts transfected with recombinant human RNASEL using RNASEL monoclonal antibody, clone 2E9 (Cat # MAB2378).
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6041
  • Gene Name:
  • Gene Alias:
  • DKFZp781D08126,MGC104972,MGC133329,PRCA1,RNS4
  • Gene Description:
  • ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
  • Gene Summary:
  • This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq
  • Other Designations:
  • 2',5'-oligoisoadenylate synthetase-dependent,OTTHUMP00000033148,interferon-induced 2-5A-dependent RNase,ribonuclease 4,ribonuclease L
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