BAP1 monoclonal antibody, clone 1G8
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of BAP1 in HeLa whole celll lysate using BAP1 monoclonal antibody, clone 1G8 (Cat # MAB2377).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant BAP1.
Immunogen
Recombinant protein corresponding to full length human BAP1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Immunocytochemistry (1:100)
Immunofluorescence (1:50-1:200)
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of BAP1 in HeLa whole celll lysate using BAP1 monoclonal antibody, clone 1G8 (Cat # MAB2377).Immunocytochemistry
Immunofluorescence
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Gene Info — BAP1
Entrez GeneID
8314Protein Accession#
Q92560Gene Name
BAP1
Gene Alias
DKFZp686N04275, FLJ35406, FLJ37180, HUCEP-13, KIAA0272, UCHL2, hucep-6
Gene Description
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Omim ID
603089Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset protein (BRCA1). This gene is thought to be a tumor suppressor gene that functions in the BRCA1 growth control pathway. There are multiple polyadenylation sites found in this gene. [provided by RefSeq
Other Designations
BRCA1 associated protein-1|cerebral protein-13|cerebral protein-6|ubiquitin carboxy-terminal hydrolase
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Interactome
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Disease
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Publication Reference
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BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
Jensen DE, Proctor M, Marquis ST, Gardner HP, Ha SI, Chodosh LA, Ishov AM, Tommerup N, Vissing H, Sekido Y, Minna J, Borodovsky A, Schultz DC, Wilkinson KD, Maul GG, Barlev N, Berger SL, Prendergast GC, Rauscher FJ 3rd.
Oncogene 1998 Mar; 16(9):1097.
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BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
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