NPM1 (phospho S4) monoclonal antibody, clone A1
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with NPM1 (phospho S4) monoclonal antibody, clone A1 (Cat # MAB23570). Lane 1: untreated or Lane 2: treated with nocodazole.
Flow Cytometry
Flow cytometric analysis of C6 cells with NPM1 (phospho S4) monoclonal antibody, clone A1 (Cat # MAB23570).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human NPM1.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding S4 of human NPM1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.1% BSA and 0.02% sodium azide).
Storage Instruction
Store at -20°C.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with NPM1 (phospho S4) monoclonal antibody, clone A1 (Cat # MAB23570). Lane 1: untreated or Lane 2: treated with nocodazole.Flow Cytometry
Flow cytometric analysis of C6 cells with NPM1 (phospho S4) monoclonal antibody, clone A1 (Cat # MAB23570). -
Gene Info — NPM1
Entrez GeneID
4869Protein Accession#
P06748Gene Name
NPM1
Gene Alias
B23, MGC104254, NPM
Gene Description
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Gene Ontology
HyperlinkGene Summary
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM
Other Designations
nucleolar phosphoprotein B23|nucleophosmin 1|nucleophosmin/nucleoplasmin family, member 1|numatrin
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Interactome
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Disease
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