JAK3 (phospho Y980/981) monoclonal antibody, clone E10 (FITC)
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Flow Cytometry
Flow cytometric analysis of Ramos cells with JAK3 (phospho Y980/981) monoclonal antibody, clone E10 (FITC) (Cat # MAB23567).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human JAK3.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Y980/981 of human Jak3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of Ramos cells with JAK3 (phospho Y980/981) monoclonal antibody, clone E10 (FITC) (Cat # MAB23567). -
Gene Info — JAK3
Entrez GeneID
3718Protein Accession#
P52333Gene Name
JAK3
Gene Alias
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Gene Description
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
Omim ID
600173Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq
Other Designations
Janus kinase 3|leukocyte Janus kinase|tyrosine-protein kinase JAK3
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Interactome
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Pathway
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Disease
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