CITED2 monoclonal antibody, clone JA22
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Specification
Product Description
Mouse monoclonal antibody raised against CITED2.
Immunogen
Human CITED2.
Host
Mouse
Reactivity
Human
Specificity
This antibody is specific to CITED 2.
Form
Liquid
Isotype
IgG1, kappa
Recommend Usage
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.09% sodium azide
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — CITED2
Entrez GeneID
10370Protein Accession#
Q99967Gene Name
CITED2
Gene Alias
MRG1, P35SRJ
Gene Description
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Omim ID
602937Gene Ontology
HyperlinkGene Summary
with Glu/Asp-rich carboxy-terminal domain
Other Designations
OTTHUMP00000017315
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Interactome
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Disease
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Publication Reference
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Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells.
Dabir P, Marinic TE, Krukovets I, Stenina OI.
Circulation Research 2008 Jun; 102(12):1558.
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CITED2 is expressed in human adrenocortical cells and regulated by basic fibroblast growth factor.
Haase M, Schott M, Bornstein SR, Malendowicz LK, Scherbaum WA, Willenberg HS.
The Journal of Endocrinology 2007 Feb; 192(2):459.
Application:ChIP, Mouse, C2C12 cells.
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Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway.
Bamforth SD, Braganca J, Farthing CR, Schneider JE, Broadbent C, Michell AC, Clarke K, Neubauer S, Norris D, Brown NA, Anderson RH, Bhattacharya S.
Nature Genetics 2004 Nov; 36(11):1189.
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Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator.
Tien ES, Davis JW, Vanden Heuvel JP.
The Journal of Biological Chemistry 2004 Jun; 279(23):24053.
Application:WB, Mouse, Mouse hepatocytes.
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Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1.
Bhattacharya S, Michels CL, Leung MK, Arany ZP, Kung AL, Livingston DM.
Genes & Development 1999 Jan; 13(1):64.
Application:IF, IP, WB-Tr, Human, Mouse, C2C12, U-2 OS cells.
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Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells.
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