DMC1 monoclonal antibody, clone 1D12/4
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot detection of DMC1 (37 kDa) from mouse testis using DMC1 monoclonal antibody, clone 1D12/4 (Cat #MAB2349) (1 : 1000).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant DMC1.
Immunogen
Recombinant His fusion protein corresponding to human DMC1.
Host
Mouse
Reactivity
Human, Mouse
Specificity
This antibody is specific to DMC-1.
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.09% sodium azide
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot detection of DMC1 (37 kDa) from mouse testis using DMC1 monoclonal antibody, clone 1D12/4 (Cat #MAB2349) (1 : 1000). -
Gene Info — DMC1
Entrez GeneID
11144Protein Accession#
Q14565Gene Name
DMC1
Gene Alias
DMC1H, HsLim15, LIM15, MGC150472, MGC150473, dJ199H16.1
Gene Description
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
Omim ID
602721Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined. [provided by RefSeq
Other Designations
DMC1 dosage suppressor of mck1 homolog|DMC1 homologue|disrupted meiotic cDNA1, yeast, homolog of|meiotic recombination protein DMC1/LIM15 homolog
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Interactome
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Disease
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Publication Reference
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Consequences of the selective blockage of chaperone-mediated autophagy.
Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM.
PNAS 2006 Apr; 103(15):5805.
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Consequences of the selective blockage of chaperone-mediated autophagy.
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