MAP2K7 (phospho S271/T275) monoclonal antibody, clone R4F9 (PE)
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More Files
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Flow Cytometry
Flow cytometric analysis of HEK 293T cells with MAP2K7 (phospho S271/T275) monoclonal antibody, clone R4F9 (PE) (Cat # MAB23449). Unstained treated with imatinib as negative control (blue) or stained treated with imatinib (red) or treated with UV plus TPA and stained (green).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human MAP2K7.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding S271/T275 of human MAP2K7.
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
PE
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of HEK 293T cells with MAP2K7 (phospho S271/T275) monoclonal antibody, clone R4F9 (PE) (Cat # MAB23449). Unstained treated with imatinib as negative control (blue) or stained treated with imatinib (red) or treated with UV plus TPA and stained (green). -
Gene Info — MAP2K7
Entrez GeneID
5609Gene Name
MAP2K7
Gene Alias
Jnkk2, MAPKK7, MKK7, PRKMK7
Gene Description
mitogen-activated protein kinase kinase 7
Omim ID
603014Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq
Other Designations
JNK kinase 2|JNK-activating kinase 2|MAP kinase kinase 7|OTTHUMP00000174397|c-Jun N-terminal kinase kinase 2|dual specificity mitogen-activated protein kinase kinase 7
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Pathway
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