INPPL1 (phospho Y1135) monoclonal antibody, clone 1D2 (FITC)
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human INPPL1.
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr1135 of human phospho Ship2
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
FITC
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/million cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% NaN3, 0.2% BSA)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells with INPPL1 (phospho Tyr1135) monoclonal antibody, clone 1D2 (FITC)(Cat # MAB23404). Untreated (red) or treated with INFa, IL-4 and pervanate (green). -
Gene Info — INPPL1
Entrez GeneID
3636Protein Accession#
O15357Gene Name
INPPL1
Gene Alias
SHIP2
Gene Description
inositol polyphosphate phosphatase-like 1
Omim ID
600829Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq
Other Designations
51C protein
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Interactome
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Pathway
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Disease
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