HNRNPM monoclonal antibody, clone 2A6
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant HNRNPM.
Immunogen
Recombinant protein corresponding to full length human HNRNPM.
Host
Mouse
Reactivity
Bovine, Human, Mouse, Pig, Rabbit, Rat
Specificity
This antibody is specific to human RNP M3-M4.
Form
Liquid
Isotype
IgG2b, kappa
Recommend Usage
Immunocytochemistry (1:1000)
Immunofluorescence (1:1000)
Immunohistochemistry (Frozen sections) (1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000)
Immunoprecipitation (1:1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.09% sodium azide
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunofluorescence
Immunoprecipitation
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Gene Info — HNRNPM
Entrez GeneID
4670Protein Accession#
P52272Gene Name
HNRNPM
Gene Alias
DKFZp547H118, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1
Gene Description
heterogeneous nuclear ribonucleoprotein M
Omim ID
160994Gene Ontology
HyperlinkGene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated. [provided by RefSeq
Other Designations
M4 protein|N-acetylglucosamine receptor 1|heterogenous nuclear ribonucleoprotein M|heterogenous nuclear ribonucleoprotein M4|hnRNA-binding protein M4
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Interactome
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Publication Reference
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The human hnRNP M proteins: identification of a methionine/arginine-rich repeat motif in ribonucleoproteins.
Datar KV, Dreyfuss G, Swanson MS.
Nucleic Acids Research 1993 Feb; 21(3):439.
Application:WB-Ce, Human, HeLa cells.
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The human hnRNP M proteins: identification of a methionine/arginine-rich repeat motif in ribonucleoproteins.
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