KIAA1524 monoclonal antibody, clone 2G10
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant KIAA1524.
Immunogen
Recombinant protein corresponding to C-terminus of the human p90 protein.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b, kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot Analysis of KIAA1524 in HeLa whole cell lysate using KIAA1524 monoclonal antibody, clone 2G10 (Cat #MAB2337).Immunofluorescence
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Gene Info — KIAA1524
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Interactome
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Publication Reference
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CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells.
Li W, Ge Z, Liu C, Liu Z, Bjorkholm M, Jia J, Xu D.
Clinical Cancer Research 2009 Jun; 14(12):3722.
Application:IHC-P, WB-Tr, Human, AGS, HCT-116 cells, Human gastric cancer.
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CIP2A inhibits PP2A in human malignancies.
Junttila MR, Puustinen P, Niemela M, Ahola R, Arnold H, Bottzauw T, Ala-aho R, Nielsen C, Ivaska J, Taya Y, Lu SL, Lin S, Chan EK, Wang XJ, Grenman R, Kast J, Kallunki T, Sears R, Kahari VM, Westermarck J.
Cell 2007 Jul; 130(1):51.
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Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Soo Hoo L, Zhang JY, Chan EK.
Oncogene 2002 Jul; 21(32):5006.
Application:IF, WB-Ce, Human, Mouse, MOLT-4, T24, HeLa, HEp-2, 3T3 cells, Keratinocytes, Serum.
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CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells.
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