Mouse monoclonal antibody raised against recombinant LMO2.
Recombinant protein corresponding to human LMO2.
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
Immunofluorescence (1:100-1:500) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:500) Western Blot (0.5 ug/mL) The optimal working dilution should be determined by the end user.
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Store at 4°C for short term. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms
LIM domain only 2,T-cell translocation gene 2,rhombotin 2,rhombotin-like 1