KRT5/KRT6A monoclonal antibody, clone T16-K

Catalog # MAB23281

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Size:7 mL
Price: USD $ 329.00
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  • +1-909-264-1399
    +1-909-992-0619
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Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil epithelium with KRT5/KRT6A monoclonal antibody, clone T16-K (Cat # MAB23281).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human epidermis with KRT5/KRT6A monoclonal antibody, clone T16-K (Cat # MAB23281).

  • Specification

    Product Description

    Rabbit monoclonal antibody raised against synthetic peptide of human KRT5/KRT6A.

    Immunogen

    A synthetic peptide corresponding to amino acids 548-564 at C-terminus of human cytokeratin 6.

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    immunoaffinity purification

    Recommend Usage

    Immunohistochemistry (1:100-1:200)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 20 mM Tris-HCl buffer, pH 8.0 (20 mg/mL BSA, 0.05% Sodium Azide).

    Storage Instruction

    Store at 4°C. Do not freeze.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil epithelium with KRT5/KRT6A monoclonal antibody, clone T16-K (Cat # MAB23281).

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human epidermis with KRT5/KRT6A monoclonal antibody, clone T16-K (Cat # MAB23281).
  • Gene Info — KRT5

    Entrez GeneID

    3852

    Protein Accession#

    P13647, P02538

    Gene Name

    KRT5

    Gene Alias

    CK5, DDD, EBS2, K5, KRT5A

    Gene Description

    keratin 5

    Omim ID

    131800 131960 148040 179850

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq

    Other Designations

    58 kda cytokeratin|epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types|keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types)|keratin, type II cytoskeletal 5

  • Gene Info — KRT6A

    Entrez GeneID

    3853

    Protein Accession#

    P13647, P02538

    Gene Name

    KRT6A

    Gene Alias

    CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D

    Gene Description

    keratin 6A

    Omim ID

    148041 167200

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq

    Other Designations

    56 cytoskeletal type II keratin|K6D keratin|cytokeratin 6A|cytokeratin 6C|cytokeratin 6D|keratin 6C|keratin, epidermal type II, K6A|keratin, epidermal type II, K6C|keratin, type II cytoskeletal 6D|type II keratin isoform K6c

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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