MAPT (phospho S396) monoclonal antibody, clone RM461
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse brain tissue lysates with MAPT (phospho S396) monoclonal antibody, clone RM461 (Cat # MAB23244) at a 1:1000 dilution. The phospho-specificity of RM461 was verified by peptide blocking using a phosphopeptide or non-phosphopeptide targeting residue Ser396.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain with MAPT (phospho S396) monoclonal antibody, clone RM461 (Cat # MAB23244) at a 1:50 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon with MAPT (phospho S396) monoclonal antibody, clone RM461 (Cat # MAB23244) at a 1:50 dilution.
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MAPT.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic phosphopeptide corresponding to residues surrounding Ser396 of human MAPT.
Reactivity
Human
Specificity
This antibody reacts to MAPT only when phosphorylated at Ser396. There is no cross-reactivity to MAPT that is not phosphorylated. This antibody reacts to human, mouse or rat Phospho-MAPT (Ser396).
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse brain tissue lysates with MAPT (phospho S396) monoclonal antibody, clone RM461 (Cat # MAB23244) at a 1:1000 dilution. The phospho-specificity of RM461 was verified by peptide blocking using a phosphopeptide or non-phosphopeptide targeting residue Ser396.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain with MAPT (phospho S396) monoclonal antibody, clone RM461 (Cat # MAB23244) at a 1:50 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon with MAPT (phospho S396) monoclonal antibody, clone RM461 (Cat # MAB23244) at a 1:50 dilution. -
Gene Info — MAPT
Entrez GeneID
4137Gene Name
MAPT
Gene Alias
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Gene Description
microtubule-associated protein tau
Gene Ontology
HyperlinkGene Summary
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq
Other Designations
G protein beta1/gamma2 subunit-interacting factor 1|microtubule-associated protein tau, isoform 4
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com