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Last updated: 2022/5/22

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HIST1H2BC (acetyl K11) monoclonal antibody, clone RM456 

  • Catalog # : MAB23240
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic acetyl peptide of human HIST1H2BC (acetyl K11).
  • Immunogen:
  • A synthetic acetyl peptide corresponding to residues surrounding K11 of HIST1H2BC.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts to HIST1H2BC acetylated at Lysine 11 (K11ac). No cross reactivity with other acetylated Lysines in histones.
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (0.001 ug/mL-0.01 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol, 1% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa cell lysates with HIST1H2BC (acetyl K11) monoclonal antibody, clone RM456 (Cat # MAB23240) at a 0.002 ug/mL dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8347
  • Gene Name:
  • HIST1H2BC
  • Gene Alias:
  • H2B.1,H2B/l,H2BFL,MGC104246,dJ221C16.3
  • Gene Description:
  • histone cluster 1, H2bc
  • Gene Summary:
  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq
  • Other Designations:
  • H2B histone family, member L,OTTHUMP00000016141,histone 1, H2bc
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