HAVCR2 monoclonal antibody, clone RM448
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Daudi cell lysates with HAVCR2 monoclonal antibody, clone RM448 (Cat # MAB23233) at a 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thymus with HAVCR2 monoclonal antibody, clone RM448 (Cat # MAB23233) at a 1:200 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung cancer with HAVCR2 monoclonal antibody, clone RM448 (Cat # MAB23233) at a 1:200 dilution.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human HAVCR2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human HAVCR2.
Reactivity
Human
Specificity
This antibody reacts to human HAVCR2 (Hepatitis A virus cellular receptor 2).
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:100-1:200)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Daudi cell lysates with HAVCR2 monoclonal antibody, clone RM448 (Cat # MAB23233) at a 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thymus with HAVCR2 monoclonal antibody, clone RM448 (Cat # MAB23233) at a 1:200 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung cancer with HAVCR2 monoclonal antibody, clone RM448 (Cat # MAB23233) at a 1:200 dilution. -
Gene Info — HAVCR2
Entrez GeneID
84868Gene Name
HAVCR2
Gene Alias
FLJ14428, KIM-3, TIM3, TIMD3, Tim-3
Gene Description
hepatitis A virus cellular receptor 2
Omim ID
606652Gene Ontology
HyperlinkGene Summary
CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM
Other Designations
T cell immunoglobulin mucin 3|T cell immunoglobulin mucin-3|kidney injury molecule-3
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Interactome
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Disease
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