PGR monoclonal antibody, clone RM434
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PGR.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against progesterone-KLH.
Reactivity
Human
Specificity
This antibody reacts to PGR.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
ELISA (1 ng/well-10 ng/well)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
Standard curve for PGR monoclonal antibody, clone RM434 (Cat # MAB23219) Competitive ELISA. -
Gene Info — PGR
Entrez GeneID
5241Gene Name
PGR
Gene Alias
NR3C3, PR
Gene Description
progesterone receptor
Omim ID
607311Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
Other Designations
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Interactome
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Disease
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