SOX2 monoclonal antibody, clone RM427
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot of 293 cell lysate using SOX2 monoclonal antibody clone RM427 at a 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin fixed and paraffin embedded human lung squamous Cell Carcinoma tissue section using SOX2 monoclonal antibody clone RM427 at a 1:100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin fixed and paraffin embedded human glioblastoma tissue section using SOX2 monoclonal antibody clone RM427 at a 1:100 dilution.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SOX2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to the C-terminus of human SOX2.
Reactivity
Human
Specificity
This antibody reacts to human SOX2.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunochemistry (1:100 - 1:250)
Western Blot (1:100 - 1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot of 293 cell lysate using SOX2 monoclonal antibody clone RM427 at a 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin fixed and paraffin embedded human lung squamous Cell Carcinoma tissue section using SOX2 monoclonal antibody clone RM427 at a 1:100 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin fixed and paraffin embedded human glioblastoma tissue section using SOX2 monoclonal antibody clone RM427 at a 1:100 dilution. -
Gene Info — SOX2
Entrez GeneID
6657Gene Name
SOX2
Gene Alias
ANOP3, MCOPS3, MGC2413
Gene Description
SRY (sex determining region Y)-box 2
Gene Ontology
HyperlinkGene Summary
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq
Other Designations
SRY-related HMG-box gene 2|sex-determining region Y-box 2|transcription factor SOX2
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Interactome
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Disease
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