ITGB3 monoclonal antibody, clone RM382
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human ITGB3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human ITGB3.
Reactivity
Human
Specificity
This antibody reacts to human ITGB3/CD61.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:250-1:500)
Western Blot (1:5000-1:25000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse spleen tissue lysates with ITGB3 monoclonal antibody, clone RM382 (Cat # MAB23164) at a 1:5000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with ITGB3 monoclonal antibody, clone RM382 (Cat # MAB23164) at a 1:500 dilution. -
Gene Info — ITGB3
Entrez GeneID
3690Gene Name
ITGB3
Gene Alias
CD61, GP3A, GPIIIa
Gene Description
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Omim ID
173470Gene Ontology
HyperlinkGene Summary
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq
Other Designations
integrin beta chain, beta 3|platelet glycoprotein IIIa
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