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Last updated: 2022/5/22

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DNTT monoclonal antibody, clone RM379 

  • Catalog # : MAB23162
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human DNTT.
  • Immunogen:
  • A synthetic peptide corresponding to human DNTT.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts to human DNTT.
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:100-1:200)
    Western Blot (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol, 1% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Jurkat cell lysates with DNTT monoclonal antibody, clone RM379 (Cat # MAB23162) at a 1:2000 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thymus with DNTT monoclonal antibody, clone RM379 (Cat # MAB23162) at a 1:200 dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1791
  • Gene Name:
  • DNTT
  • Gene Alias:
  • TDT
  • Gene Description:
  • deoxynucleotidyltransferase, terminal
  • Gene Summary:
  • This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq
  • Other Designations:
  • DNA nucleotidylexotransferase,OTTHUMP00000020171,nucleosidetriphosphate:DNA deoxynucleotidylexotransferase,terminal addition enzyme,terminal deoxynucleotidyltransferase,terminal deoxyribonucleotidyltransferase,terminal transferase
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