Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung squamous cell carcinoma with KRT5/KRT6 monoclonal antibody, clone RM341 (Cat # MAB23158) at a 1:1000 dilution.
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with KRT5/KRT6 monoclonal antibody, clone RM341 (Cat # MAB23158) at a 1:1000 dilution.
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervix with KRT5/KRT6 monoclonal antibody, clone RM341 (Cat # MAB23158) at a 1:1000 dilution.
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
Other Designations:
58 kda cytokeratin,epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types,keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types),keratin, type II cytoskeletal 5