Western blot analysis of Lane 1: 293T cell lysate, Lane 2: HepG2 cell lysate, Lane 3: U-251 MG cell lysate, Lane 4: rat kidney tissue lysate using DDAH1 monoclonal antibody, clone ARC1043 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq