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Last updated: 2021/4/11

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CDK8 monoclonal antibody, clone ARC1682 

  • Catalog # : MAB23068
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CDK8.
  • Immunogen:
  • A synthetic peptide corresponding to human CDK8.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 53
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: mouse brain, Lane 2: rat liver, Lane 3: rat brain using CDK8 monoclonal antibody, clone ARC1682 (Cat # MAB23068) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1024
  • Gene Name:
  • CDK8
  • Gene Alias:
  • K35,MGC126074,MGC126075
  • Gene Description:
  • cyclin-dependent kinase 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq
  • Other Designations:
  • CDK8 protein kinase,OTTHUMP00000018158,cell division protein kinase 8,protein kinase K35
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