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CTTN monoclonal antibody, clone ARC1613 

  • Catalog # : MAB23041
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CTTN.
  • Immunogen:
  • A synthetic peptide corresponding to human CTTN.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 80
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Immunohistochemistry (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: HeLa, Lane 2: 293T, Lane 3: HUVEC, Lane 4: mouse lung using CTTN monoclonal antibody, clone ARC1613 (Cat # MAB23041) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of mouse testis using CTTN monoclonal antibody, clone ARC1613 (Cat # MAB23041) at dilution of 1:100 (40x lens).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of rat testis using CTTN monoclonal antibody, clone ARC1613 (Cat # MAB23041) at dilution of 1:100 (40x lens).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human esophageal using CTTN monoclonal antibody, clone ARC1613 (Cat # MAB23041) at dilution of 1:100 (40x lens).
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of C6 cells using CTTN monoclonal antibody, clone ARC1613 (Cat # MAB23041) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of U-2 OS cells using CTTN monoclonal antibody, clone ARC1613 (Cat # MAB23041) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of NIH/3T3 cells using CTTN monoclonal antibody, clone ARC1613 (Cat # MAB23041) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2017
  • Gene Name:
  • CTTN
  • Gene Alias:
  • EMS1,FLJ34459
  • Gene Description:
  • cortactin
  • Gene Summary:
  • This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • 1110020L01Rik,ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate),oncogene EMS1
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  • Interactome
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