Rabbit monoclonal antibody raised against synthetic peptide of human UBE2N.
Immunogen:
A synthetic peptide corresponding to human UBE2N.
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Form:
Liquid
Purification:
Affinity purification
Isotype:
IgG
Recommend Usage:
Immunofluorescence (1:50-1:200) Immunohistochemistry (1:50-1:200) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq
Other Designations:
bendless-like ubiquitin conjugating enzyme,ubiquitin carrier protein N,ubiquitin-conjugating enzyme E2N,ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13),ubiquitin-protein ligase N,yeast UBC13 homolog