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IMPDH2 monoclonal antibody, clone ARC1479 

  • Catalog # : MAB23020
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human IMPDH2.
  • Immunogen:
  • A synthetic peptide corresponding to human IMPDH2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) HeLa, (2) HepG2, (3) A-549, (4) K-562 cell lysates, (5) rat spleen.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of C6 cells. Blue: DAPI for nuclear staining.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of U-2 OS cells. Blue: DAPI for nuclear staining.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of NIH/3T3 cells. Blue: DAPI for nuclear staining.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3615
  • Gene Name:
  • IMPDH2
  • Gene Alias:
  • IMPD2,IMPDH-II
  • Gene Description:
  • IMP (inosine monophosphate) dehydrogenase 2
  • Gene Summary:
  • This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq
  • Other Designations:
  • IMP dehydrogenase 2,IMP oxireductase 2,inosine 5' phosphate dehydrogenase 2,inosine monophosphate dehydrogenase 2,inosine monophosphate dehydrogenase type II,inosine monophosphate oxireductase 2
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