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Last updated: 2021/1/17

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FHIT monoclonal antibody, clone ARC1401 

  • Catalog # : MAB22996
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human FHIT.
  • Immunogen:
  • A synthetic peptide corresponding to human FHIT.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) HepG2 cell lysates, (2) rat liver, (3) rat spleen.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2272
  • Gene Name:
  • FHIT
  • Gene Alias:
  • AP3Aase,FRA3B
  • Gene Description:
  • fragile histidine triad gene
  • Gene Summary:
  • This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. [provided by RefSeq
  • Other Designations:
  • AP3A hydrolase,bis(5'-adenosyl)-triphosphatase,diadenosine 5',5'''-P1,P3-triphosphate hydrolase,dinucleosidetriphosphatase,tumor suppressor protein
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