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PC monoclonal antibody, clone ARC1371 

  • Catalog # : MAB22982
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human PC.
  • Immunogen:
  • A synthetic peptide corresponding to human PC.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 130
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: HepG2 cell lysate, Lane 2: mouse liver tissue lysate, Lane 3: mouse brain tissue lysate, Lane 4: mouse kidney tissue lysate, Lane 5: rat liver tissue lysate using PC monoclonal antibody, clone ARC1371 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 5091
  • Gene Name:
  • PC
  • Gene Alias:
  • PCB
  • Gene Description:
  • pyruvate carboxylase
  • Gene Summary:
  • This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq
  • Other Designations:
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