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HNRNPC monoclonal antibody, clone ARC1366 

  • Catalog # : MAB22981
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human HNRNPC.
  • Immunogen:
  • A synthetic peptide corresponding to human HNRNPC.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 42
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: HeLa cell lysate, Lane 2: Jurkat cell lysate, Lane 3: mouse thymus tissue lysate using HNRNPC monoclonal antibody, clone ARC1366 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of U-2 OS cells using HNRNPC monoclonal antibody, clone ARC1366 at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3183
  • Gene Name:
  • HNRNPC
  • Gene Alias:
  • C1,C2,HNRNP,HNRPC,MGC104306,MGC105117,MGC117353,MGC131677,SNRPC
  • Gene Description:
  • heterogeneous nuclear ribonucleoprotein C (C1/C2)
  • Gene Summary:
  • This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • heterogeneous nuclear ribonucleoprotein C,nuclear ribonucleoprotein particle C1 protein,nuclear ribonucleoprotein particle C2 protein
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