Rabbit monoclonal antibody raised against synthetic peptide of human FABP2.
Immunogen:
A synthetic peptide corresponding to human FABP2.
Host:
Rabbit
Theoretical MW (kDa):
15
Reactivity:
Human, Mouse, Rat
Form:
Liquid
Purification:
Affinity purification
Isotype:
IgG
Recommend Usage:
Immunofluorescence (1:50-1:200) Immunohistochemistry (1:50-1:200) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Western blot analysis of Lane 1: mouse small intestine tissue lysate, Lane 2: rat small intestine tissue lysate using FABP2 monoclonal antibody, clone ARC1343 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Immunohistochemistry of (A) rat intestine and (B) mouse intestin using FABP2 monoclonal antibody, clone ARC1343 at dilution of 1:100 (40x lens).
Immunofluorescence
Immunofluorescence analysis of mouse intestin using FABP2 monoclonal antibody, clone ARC1343 at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq
Other Designations:
Fatty acid-binding protein, intestinal,intestinal fatty acid binding protein 2