Western blot analysis of Lane 1: mouse skeletal muscle tissue lysate, Lane 2: mouse heart tissue lysate, Lane 3: rat heart tissue lysate using FABP3 monoclonal antibody, clone ARC1302 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Immunofluorescence
Immunofluorescence analysis of mouse heart using FABP3 monoclonal antibody, clone ARC1302 at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq
Other Designations:
Fatty acid-binding protein 3, muscle,OTTHUMP00000003898,fatty acid binding protein 11,fatty acid binding protein 3,mammary-derived growth inhibitor