SLC5A7 monoclonal antibody, clone 62-2E8
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More Files
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Immunohistochemistry
Immunohistochemical staining of SLC5A7 on rat basal forebrain with SLC5A7 monoclonal antibody, clone 62-2E8 (Cat # MAB2295).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant SLC5A7.
Immunogen
Recombinant protein corresponding to C-terminus of human SLC5A7.
Host
Mouse
Reactivity
Human, Mouse, Rat
Form
Liquid
Isotype
IgG1
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500)
Immunohistochemistry (Frozen sections) (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Immunohistochemistry
Immunohistochemical staining of SLC5A7 on rat basal forebrain with SLC5A7 monoclonal antibody, clone 62-2E8 (Cat # MAB2295). -
Gene Info — SLC5A7
Entrez GeneID
60482Gene Name
SLC5A7
Gene Alias
CHT, CHT1, MGC126299, MGC126300, hCHT
Gene Description
solute carrier family 5 (choline transporter), member 7
Omim ID
608761Gene Ontology
HyperlinkGene Summary
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM
Other Designations
high affinity choline transporter; hemicholinium-3-sensitive choline transporter
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Interactome
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Disease
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Publication Reference
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Vesicular localization and activity-dependent trafficking of presynaptic choline transporters.
Ferguson SM, Savchenko V, Apparsundaram S, Zwick M, Wright J, Heilman CJ, Yi H, Levey AI, Blakely RD.
The Journal of Neuroscience 2003 Oct; 23(30):9697.
Application：IHC, IF, WB-Ti, Mouse, Brain, Spinal cord, Brainstem, Midbrain, Hippocampus, Cortex, Cerebellum, Striatum, Kidney.
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Vesicular localization and activity-dependent trafficking of presynaptic choline transporters.
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