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Last updated: 2021/1/17

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ATG4B monoclonal antibody, clone ARC1264 

  • Catalog # : MAB22896
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human ATG4B.
  • Immunogen:
  • A synthetic peptide corresponding to human ATG4B.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) HepG2, (2) RD, (3) Jurkat cell lysates, (4) mouse testis, (5) mouse brain, (6) rat lung, (7) rat brain.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of NIH/3T3 cells. Blue: DAPI for nuclear staining.
  • Application Image
  • Gene Information
  • Gene Name:
  • ATG4B
  • Gene Alias:
  • APG4B,AUTL1,MGC1353
  • Gene Description:
  • ATG4 autophagy related 4 homolog B (S. cerevisiae)
  • Gene Summary:
  • Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • APG4 autophagy 4 homolog B,autophagin-1
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