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SNCA/SNCB monoclonal antibody, clone ARC1181 

  • Catalog # : MAB22886
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human SNCA/SNCB.
  • Immunogen:
  • A synthetic peptide corresponding to human SNCA/SNCB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (0.05% BSA, 50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate) analysis of (1) mouse brain, (2) rat brain.
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate) analysis of extracts of U87 MG cell lysates.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of rat brain. Blue: DAPI for nuclear staining.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6622
  • Protein Accession#:
  • P37840; Q16143
  • Gene Name:
  • SNCA
  • Gene Alias:
  • MGC110988,NACP,PARK1,PARK4,PD1
  • Gene Description:
  • synuclein, alpha (non A4 component of amyloid precursor)
  • Gene Summary:
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161559,OTTHUMP00000161561,alpha synuclein,alpha-synuclein,alpha-synuclein, isoform NACP140,non A-beta component of AD amyloid,non A4 component of amyloid
  • Gene Information
  • Entrez GeneID:
  • 6620
  • Protein Accession#:
  • P37840; Q16143
  • Gene Name:
  • SNCB
  • Gene Alias:
  • -
  • Gene Description:
  • synuclein, beta
  • Other Designations:
  • beta-synuclein
  • Interactome
  • Interactome
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