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Last updated: 2020/8/2

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CCR8 monoclonal antibody, clone ARC0956 

  • Catalog # : MAB22853
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CCR8.
  • Immunogen:
  • A synthetic peptide corresponding to human CCR8.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 41
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: A-549 cell lysate, Lane 2: A-431 cell lyste, Lane 3: mouse lung tissue lysate, Lane 4: mouse thymus tissue lysate, using CCR8 monoclonal antibody, clone ARC0956 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of Jurkat cells using CCR8 monoclonal antibody, clone ARC0956 at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1237
  • Gene Name:
  • CCR8
  • Gene Alias:
  • CDw198,CKR-L1,CKRL1,CMKBR8,CMKBRL2,CY6,GPR-CY6,MGC129966,MGC129973,TER1
  • Gene Description:
  • chemokine (C-C motif) receptor 8
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq
  • Other Designations:
  • CC chemokine receptor 8,CC-chemokine receptor chemr1,chemokine (C-C) receptor 8,chemokine (C-C) receptor-like 2
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