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MRE11A monoclonal antibody, clone ARC0931 

  • Catalog # : MAB22846
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human MRE11A.
  • Immunogen:
  • A synthetic peptide corresponding to human MRE11A.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 81
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: HeLa cell lysate, Lane 2: mouse testis tissue lysate, using MRE11A monoclonal antibody, clone ARC0931 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 4361
  • Gene Name:
  • MRE11A
  • Gene Alias:
  • ATLD,HNGS1,MRE11,MRE11B
  • Gene Description:
  • MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • AT-like disease,DNA recombination and repair protein,double-strand break repair protein MRE11A,endo/exonuclease Mre11,meiotic recombination 11 homolog A
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