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TREX1 monoclonal antibody, clone ARC0841 

  • Catalog # : MAB22812
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human TREX1.
  • Immunogen:
  • A synthetic peptide corresponding to human TREX1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 33
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Lane 1: HeLa cell lysate, Lane 2: HT-29 cell lysate, Land 3: Jurkat cell lysate, using TREX1 monoclonal antibody, clone ARC0841 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • TREX1
  • Gene Alias:
  • AGS1,AGS5,CRV,DKFZp434J0310,DRN3,HERNS
  • Gene Description:
  • three prime repair exonuclease 1
  • Gene Summary:
  • This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 3' repair exonuclease 1,OTTHUMP00000164813,deoxyribonuclease III, dnaQ/mutD-like
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