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SMARCE1 monoclonal antibody, clone ARC0839 

  • Catalog # : MAB22811
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human SMARCE1.
  • Immunogen:
  • A synthetic peptide corresponding to human SMARCE1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 57
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of Lane 1: mouse spinal cord tissue lysate, Lane 2: mouse brain tissue lysate, Lane 3: rat brain tissue lysate.
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Lane 1: HeLa cell lysate, Lane 2: MCF7 cell lysate, Lane 3: Jurkat cell lysate.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of U-2 OS cells using SMARCE1 monoclonal antibody, clone ARC0839 at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6605
  • Gene Name:
  • SMARCE1
  • Gene Alias:
  • BAF57
  • Gene Description:
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • Gene Summary:
  • The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq
  • Other Designations:
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1,mammalian chromatin remodeling complex BRG1-associated factor 57
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