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Last updated: 2020/8/9

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UCHL1 monoclonal antibody, clone 10A1 

  • Catalog # : MAB22782
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human UCHL1.
  • Immunogen:
  • Recombinant fusion protein corresponding to full length human UCHL1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Human protein gene product 9.5.
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:40 for 30 minutes at 25°C)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do not freeze. Return to 2-8°C immediately after use. Do not use after expiration date indicated on the vial label.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Recommended positive control tissue is small bowel where enteric ganglion cells stain.
    Recommended negative control tissue is tonsil where the lymphoid cells are negative.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon. Note the staining in the neuronal elements and the ganglia of the longitudinal and circular smooth muscle.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7345
  • Gene Name:
  • UCHL1
  • Gene Alias:
  • PARK5,PGP9.5,Uch-L1
  • Gene Description:
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
  • Gene Summary:
  • The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease
  • Other Designations:
  • ubiquitin C-terminal esterase L1,ubiquitin carboxyl-terminal esterase L1,ubiquitin thiolesterase L1
  • Gene Pathway
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