SGCB monoclonal antibody, clone BETASARC1/5B1
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human SGCB.
Immunogen
Recombinant fusion protein corresponding to N-terminus of human SGCB.
Host
Mouse
Reactivity
Human
Specificity
Human beta-sarcoglycan (43 kD).
Form
Liquid
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Frozen sections) (1:50-1:200 for 60 minutes at 25°C)
The optimal working dilution should be determined by the end user.Storage Buffer
In tissue culture supernatant (0.09% sodium azide).
Storage Instruction
Store at 4°C. Do not freeze. Return to 2-8°C immediately after use. Do not use after expiration date indicated on the vial label.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Recommended positive control tissue is skeletal muscle. -
Applications
Immunohistochemistry (Frozen sections)
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Gene Info — SGCB
Entrez GeneID
6443Gene Name
SGCB
Gene Alias
A3b, LGMD2E, SGC
Gene Description
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy
Other Designations
OTTHUMP00000158880|beta-sarcoglycan(43kD dystrophin-associated glycoprotein)|limb girdle muscular dystrophy 2E (non-linked families)|sarcoglycan, beta|sarcoglycan, beta (43kD dystrophin-associated glycoprotein)
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Interactome
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Pathway
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