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Last updated: 2020/8/9

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BCL2 monoclonal antibody, clone bcl-2/100/D5 

  • Catalog # : MAB22774
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of human BCL2.
  • Immunogen:
  • A synthetic peptide corresponding to human BCL2.
  • Sequence:
  • GAAPAPGIFSSQPGC-COOH
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Human bcl-2 oncoprotein.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100 for 30 minutes at 25°C)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do not freeze. Return to 2-8°C immediately after use. Do not use after expiration date indicated on the vial label.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Recommended positive control tissue is kidney
    Recommended negative control tissue is cerebellum.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human follicular lymphoma: neoplastic cells show a moderate, predominantly cytoplasmic staining reaction.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 596
  • Gene Name:
  • BCL2
  • Gene Alias:
  • Bcl-2
  • Gene Description:
  • B-cell CLL/lymphoma 2
  • Gene Summary:
  • This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq
  • Other Designations:
  • B-cell lymphoma protein 2,OTTHUMP00000163680
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