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IGF2R monoclonal antibody, clone ARC0263 

  • Catalog # : MAB22703
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human IGF2R.
  • Immunogen:
  • A synthetic peptide corresponding to human IGF2R.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate) analysis of mouse heart.
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate) analysis of extracts of A-549 cell lysates.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of C6 cells. Blue: DAPI for nuclear staining.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of NIH/3T3 cells. Blue: DAPI for nuclear staining.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3482
  • Gene Name:
  • IGF2R
  • Gene Alias:
  • CD222,CIMPR,M6P-R,MPR1,MPRI
  • Gene Description:
  • insulin-like growth factor 2 receptor
  • Gene Summary:
  • The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. In mice, the homologous gene is expressed only from the maternal chromosome. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017536,cation-independent mannose-6 phosphate receptor,insulin-like growth factor-2 receptor (mannose-6-phosphate receptor, cation-independent)
  • Gene Pathway
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