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Last updated: 2020/8/2

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CYBB monoclonal antibody, clone ARC0181 

  • Catalog # : MAB22650
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CYBB.
  • Immunogen:
  • A synthetic peptide corresponding to human CYBB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate) analysis of (1) mouse spleen, (2) mouse heart, (3) rat lung, (4) rat spleen.
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) HepG2, (2) Raji cell lysates, (3) HL-60 cell lysates, (4) mouse lung.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1536
  • Gene Name:
  • CYBB
  • Gene Alias:
  • CGD,GP91-1,GP91-PHOX,GP91PHOX,NOX2,p91-PHOX
  • Gene Description:
  • cytochrome b-245, beta polypeptide
  • Gene Summary:
  • Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031915,cytochrome b-245 beta polypeptide
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