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PPARGC1A/PPARGC1B monoclonal antibody, clone ARC0153 

  • Catalog # : MAB22640
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human PPARGC1A/PPARGC1B.
  • Immunogen:
  • A synthetic peptide corresponding to human PPARGC1A/PPARGC1B.
  • Host:
  • Rabbit
  • Reactivity:
  • Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) mouse liver, (2) rat heart.
  • Application Image
  • Gene Information
  • Protein Accession#:
  • Q9UBK2; Q86YN6
  • Gene Name:
  • PPARGC1A
  • Gene Alias:
  • LEM6,PGC-1(alpha),PGC-1v,PGC1,PGC1A,PPARGC1
  • Gene Description:
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
  • Gene Summary:
  • The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000123372,PPAR gamma coactivator variant form,PPAR gamma coactivator-1,ligand effect modulator-6,peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
  • Gene Information
  • Protein Accession#:
  • Q9UBK2; Q86YN6
  • Gene Name:
  • PPARGC1B
  • Gene Alias:
  • ERRL1,PERC,PGC-1(beta),PGC1B
  • Gene Description:
  • peroxisome proliferator-activated receptor gamma, coactivator 1 beta
  • Other Designations:
  • PGC-1-related estrogen receptor alpha coactivator,peroxisome proliferative activated receptor, gamma, coactivator 1, beta
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