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Last updated: 2020/8/9

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DNMT3A monoclonal antibody, clone ARC0138 

  • Catalog # : MAB22635
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human DNMT3A.
  • Immunogen:
  • A synthetic peptide corresponding to human DNMT3A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate) analysis of extracts from (1) control, (2) Dnmt3a knockout HEK 293T cell lysates.
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) K-562 cell lysates, (2) mouse thymus, (3) mouse testis, (4) rat testis.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1788
  • Gene Name:
  • DNMT3A
  • Gene Alias:
  • DNMT3A2,M.HsaIIIA
  • Gene Description:
  • DNA (cytosine-5-)-methyltransferase 3 alpha
  • Gene Summary:
  • CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • DNA MTase HsaIIIA,DNA cytosine methyltransferase 3 alpha,DNA cytosine methyltransferase 3A2,DNA methyltransferase HsaIIIA,OTTHUMP00000120005,OTTHUMP00000120006
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